Multidrug resistance in Gram-negative bacteria represents a major public health challenge, with these organisms evolving a myriad of mechanisms to evade the effects of antibiotic treatment. One ...

Could a gene regulatory network in gut microbes have evolved its elaborate and tightly regulated molecular machinery only to pump out antibiotics indiscriminately? Researchers show this is an ...

AMES, Iowa – Edward Yu took note of the facts – nearly 2 million deaths each year, 9 million infected each year, developments of multidrug-resistant, extensively drug-resistant and now totally ...

Carrying multiple copies of antibiotic-resistance genes could be key to resistance spread and evolution in bacteria, particularly those in humans and livestock. Researchers at Duke University (NC, USA ...

Antibiotics are widely considered one of the most important advances in the history of medicine. Their introduction into clinical practice during the 1940s marked a major milestone in the control of ...

Extensive application of the weed killer in Argentina may be unintentionally selecting for bacteria already resistant to many ...

Adaptive drug resistance represents one of the most critical barriers to durable responses in cancer therapy. Unlike static genetic resistance, adaptive ...