BCR-ABL induces chronic myeloid leukemia (CML) through the aberrant regulation of multiple signaling substrates. Previous research has shown that BCR-ABL mediates down-modulation of CBL-B protein ...
Our Molm-14 xenograft studies show systematic functional alterations in murine stromal and hematopoietic cell populations, with evidence for in vivo transfer of human RNA transcripts. We replicated ...