One of the biggest risk factors for developing liver cancer is a high-fat diet. A new study from MIT reveals how a fatty diet ...

Liver cells exposed to a high fat diet revert to an immature state that is more susceptible to cancer-causing mutations.

One of the biggest risk factors for developing liver cancer is a high-fat diet. A new study from MIT reveals how a fatty diet ...

(A) Distinct phases of APAP-ALF. (B) Integrative multimodal approaches, including single-nucleus RNA sequencing spatial transcriptomics, four-dimensional intravital imaging and lineage tracing in both ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

A fatty diet doesn’t just damage the liver — it rewires its cells in ways that give cancer a dangerous head start.

In a new study published in the Journal of Hepatology, researchers from the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) show that only 15–20% of hepatocytes in newborn mice - dubbed ...

Three-dimensional multicellular human liver model: For the first time, a 3D human organoid model, developed with liver tissue ...

Differentiated hepatocyte organoids formed networks of small canals that allowed bile acid to pass, in a manner similar to human tissue. While organoids aim to mimic human organs, the liver’s ...

Hepatitis B virus (HBV) infects more than 250 million people worldwide and can lead to chronic liver disease and liver cancer ...