New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative options. After research conducted as ...

While treatment options for the inherited blood disease have long been available, scientists now believe that a cure for sickle cell may lie in gene-editing.

The U.S. Food and Drug Administration (FDA) on Friday announced that it has approved Casgevy, the first CRISPR gene-editing therapy for sickle cell disease, paving the way for thousands of patients in ...

Now, following up on that success, a large Chinese collaboration has followed up with a description of an improved gene ...

LOS ANGELES (KABC) -- It's been more than a month since the FDA approved two milestone gene-editing treatments for sickle cell disease, but lining up patients for these therapies will be a challenge ...

Durable expression of anti-sickling fetal hemoglobin and reduction in sickle hemoglobin ob ...

Key points Sickle cell disease (SCD) occurs when a DNA base pair substitution in the β-globin gene results in the formation of hemoglobin S, which polymerizes when deoxygenated, leading to deformation ...

The same gene-editing technology Temple used to eliminate HIV in mice is being tested for removing sickle cell disease in humans and researchers say this is a really promising technology. This is the ...

USA: In an interim analysis of the phase I/II BEACON study, treatment with ristoglogene autogetemcel (risto-cel) demonstrated ...

Gene therapy has long promised to provide a solution for genetic blood disorders, but delivering on that promise has proven complex due to challenges including difficulties delivering the editing ...