Multi-mode chromatography has come to prominence in recent years due to the general utility of multi-mode ligands for product capture and polishing. In particular, their application in flow-through ...
Next-generation manufacturing of monoclonal antibodies (mAbs) will rely on continuous processes featuring single-use adsorbents, small-footprint production, and minimal aqueous buffer volumes, ...
Efforts to raise protein-expression levels have succeeded mightily, but at a cost. Today, high protein titers and accompanying impurity levels have come to dominate downstream processing. “We have ...