IN potassium-deficient rats characteristic granules appear within the cytoplasm of the collecting tubule cells; the origin and nature of the granules have not been established. By labelling the serum ...

Liddle syndrome is an autosomal dominant disorder caused by hyperactivity of the amiloride-sensitive sodium channel (ENaC) of the principal cell of the cortical collecting tubule. In 1963, Liddle ...

Joint research, led by Kumamoto University in Japan, has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. ADPKD is a ...

THE ever-increasing number of case reports of renal complications in sulfonamide drug therapy indicates that neither the mechanism of their production nor the means of preventing them is yet ...